About

Welcome to Pathology Imagebase, a tool for standardization of urological pathology. This website was set up by prof 0, The Karolinska Institute, during his presidency of the International Society of Urological Pathology. A panel of leading international experts in uropathology (listed under About) uploaded representative microphotographs of urological pathology. The images underwent independent review by the panel members and consensus cases are presented here. Our purpose was to obtain an international reference for grading and tumor classification. We hope that this tool will serve as an educational tool for pathologists all over the world and help to improve the quality of healthcare for patients with urological cancer.

Imagebase has been described in several publications and also been used as a reference in numerous studies.

Pathology Imagebase – a reference image database for standardization of pathology.
Egevad L, Cheville J, Evans AJ, Hörnblad J, Kench JG, Kristiansen G, Leite KRM, Magi-Galluzzi C, Pan CC, Samaratunga H, Srigley JR, True L, Zhou M, Clements M, Delahunt B; ISUP Pathology Imagebase Expert Panel.
Histopathology. 2017 Nov;71(5):677-685

Utility of Pathology Imagebase for standardisation of prostate cancer grading.
Egevad L, Delahunt B, Berney DM, Bostwick DG, Cheville J, Comperat E, Evans AJ, Fine SW, Grignon DJ, Humphrey PA, Hörnblad J, Iczkowski KA, Kench JG, Kristiansen G, Leite KRM, Magi-Galluzzi C, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, True LD, Tsuzuki T, van der Kwast T, Varma M, Zhou M, Clements M.
Histopathology. 2018 Jul;73(1):8-18.

Identification of areas of grading difficulties in prostate cancer and comparison with artificial intelligence assisted grading.
Egevad L, Swanberg D, Delahunt B, Ström P, Kartasalo K, Olsson H, Berney DM, Bostwick DG, Evans AJ, Humphrey PA, Iczkowski KA, Kench JG, Kristiansen G, Leite KRM, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, Tsuzuki T, van der Kwast T, Varma M, Zhou M, Clements M, Eklund M.
Virchows Arch. 2020 Dec;477(6):777-786.

Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.
Ström P, Kartasalo K, Olsson H, Solorzano L, Delahunt B, Berney DM, Bostwick DG, Evans AJ, Grignon DJ, Humphrey PA, Iczkowski KA, Kench JG, Kristiansen G, van der Kwast TH, Leite KRM, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, Tsuzuki T, Varma M, Zhou M, Lindberg J, Lindskog C, Ruusuvuori P, Wählby C, Grönberg H, Rantalainen M, Egevad L, Eklund M.
Lancet Oncol. 2020 Feb;21(2):222-232.

Artificial intelligence assistance significantly improves Gleason grading of prostate biopsies by pathologists.
Bulten W, Balkenhol M, Belinga JA, Brilhante A, Çakır A, Egevad L, Eklund M, Farré X, Geronatsiou K, Molinié V, Pereira G, Roy P, Saile G, Salles P, Schaafsma E, Tschui J, Vos AM; ISUP Pathology Imagebase Expert Panel; van Boven H, Vink R, van der Laak J, Hulsbergen-van der Kaa C, Litjens G.
Mod Pathol. 2021 Mar;34(3):660-671.

Estimating diagnostic uncertainty in artificial intelligence assisted pathology using conformal prediction.
Olsson H, Kartasalo K, Mulliqi N, Capuccini M, Ruusuvuori P, Samaratunga H, Delahunt B, Lindskog C, Janssen EAM, Blilie A; ISUP Prostate Imagebase Expert Panel; Egevad L, Spjuth O, Eklund M.
Nat Commun. 2022 Dec 15;13(1):7761.

PROSTATE EXPERT PANEL

0 (Panel Leader)
Sweden

Dan Berney
United Kingdom

0
USA

0
France

0
New Zealand

Andrew Evans
Canada

0
USA

0
USA

Peter Humphrey
USA

0
USA

0
Australia

0
Germany

0
Brazil

0
USA

0
USA

0
United Kingdom

0
Taiwan

Hemamali Samaratunga
Australia

0
Canada

Hiroyuki Takahashi
Japan

Toyonori Tsuzuki
Japan

Theo van der Kwast
Canada

0
United Kingdom

0
USA

BLADDER EXPERT PANEL

0 (Panel Leader)
USA

Mahul Amin
USA

0
USA

John Cheville
USA

0
France

0
New Zealand

0
USA

0
USA

Donna Hansel
USA

0
Germany

0
Germany

Lakshmi Kunju
USA

0
Brazil

0
Spain

0
USA

George Netto
USA

Gladell Paner
USA

Chin Chen Pan
Taiwan

Hemamali Samaratunga
Australia

Jonathan Shanks
UK

Fabio Tavora
USA

Xiaodong Teng
China

Toyonori Tsuzuki
Japan

0
USA

KIDNEY EXPERT PANEL

0 (Panel Leader)
New Zealand

Mahul Amin
USA

Pete Argani
USA

Matteo Brunelli
Italy

Yingbei Chen
USA

John Cheville
USA

0
France

John Eble
USA

Andrew Evans
Canada

Stuart Fleming
UK

0
USA

Ondrej Hes
Czech republic

0
Brazil

0
USA

Guido Martignoni
Italy

0
USA

Holger Moch
Switzerland

0
Taiwan

Hemamali Samaratunga
Australia

Isabell Sesterhenn
USA

0
Canada

Fabio Tavora
USA

Satish Tickoo
USA

0
USA