Welcome to Pathology Imagebase, a tool for standardization of urological pathology. This website was set up by prof Lars Egevad, The Karolinska Institute, during his presidency of the International Society of Urological Pathology. A panel of leading international experts in uropathology (listed under About) uploaded representative microphotographs of urological pathology. The images underwent independent review by the panel members and consensus cases are presented here. Our purpose was to obtain an international reference for grading and tumor classification. We hope that this tool will serve as an educational tool for pathologists all over the world and help to improve the quality of healthcare for patients with urological cancer.
Imagebase has been described in several publications and also been used as a reference in numerous studies.
Pathology Imagebase – a reference image database for standardization of pathology.
Egevad L, Cheville J, Evans AJ, Hörnblad J, Kench JG, Kristiansen G, Leite KRM, Magi-Galluzzi C, Pan CC, Samaratunga H, Srigley JR, True L, Zhou M, Clements M, Delahunt B; ISUP Pathology Imagebase Expert Panel.
Histopathology. 2017 Nov;71(5):677-685
Utility of Pathology Imagebase for standardisation of prostate cancer grading.
Egevad L, Delahunt B, Berney DM, Bostwick DG, Cheville J, Comperat E, Evans AJ, Fine SW, Grignon DJ, Humphrey PA, Hörnblad J, Iczkowski KA, Kench JG, Kristiansen G, Leite KRM, Magi-Galluzzi C, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, True LD, Tsuzuki T, van der Kwast T, Varma M, Zhou M, Clements M.
Histopathology. 2018 Jul;73(1):8-18.
Identification of areas of grading difficulties in prostate cancer and comparison with artificial intelligence assisted grading.
Egevad L, Swanberg D, Delahunt B, Ström P, Kartasalo K, Olsson H, Berney DM, Bostwick DG, Evans AJ, Humphrey PA, Iczkowski KA, Kench JG, Kristiansen G, Leite KRM, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, Tsuzuki T, van der Kwast T, Varma M, Zhou M, Clements M, Eklund M.
Virchows Arch. 2020 Dec;477(6):777-786.
Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.
Ström P, Kartasalo K, Olsson H, Solorzano L, Delahunt B, Berney DM, Bostwick DG, Evans AJ, Grignon DJ, Humphrey PA, Iczkowski KA, Kench JG, Kristiansen G, van der Kwast TH, Leite KRM, McKenney JK, Oxley J, Pan CC, Samaratunga H, Srigley JR, Takahashi H, Tsuzuki T, Varma M, Zhou M, Lindberg J, Lindskog C, Ruusuvuori P, Wählby C, Grönberg H, Rantalainen M, Egevad L, Eklund M.
Lancet Oncol. 2020 Feb;21(2):222-232.
Artificial intelligence assistance significantly improves Gleason grading of prostate biopsies by pathologists.
Bulten W, Balkenhol M, Belinga JA, Brilhante A, Çakır A, Egevad L, Eklund M, Farré X, Geronatsiou K, Molinié V, Pereira G, Roy P, Saile G, Salles P, Schaafsma E, Tschui J, Vos AM; ISUP Pathology Imagebase Expert Panel; van Boven H, Vink R, van der Laak J, Hulsbergen-van der Kaa C, Litjens G.
Mod Pathol. 2021 Mar;34(3):660-671.
Estimating diagnostic uncertainty in artificial intelligence assisted pathology using conformal prediction.
Olsson H, Kartasalo K, Mulliqi N, Capuccini M, Ruusuvuori P, Samaratunga H, Delahunt B, Lindskog C, Janssen EAM, Blilie A; ISUP Prostate Imagebase Expert Panel; Egevad L, Spjuth O, Eklund M.
Nat Commun. 2022 Dec 15;13(1):7761.
PROSTATE EXPERT PANEL
Lars Egevad (Panel Leader)
Sweden
Dan Berney
United Kingdom
David Bostwick
USA
Eva Comperat
France
Brett Delahunt
New Zealand
Andrew Evans
Canada
Samson Fine
USA
David Grignon
USA
Peter Humphrey
USA
Kenneth Iczkowski
USA
James Kench
Australia
Glen Kristiansen
Germany
Katia Leite
Brazil
Cristina Magi-Galluzzi
USA
Jesse McKenney
USA
Jon Oxley
United Kingdom
Chin-Chen Pan
Taiwan
Hemamali Samaratunga
Australia
John Srigley
Canada
Hiroyuki Takahashi
Japan
Toyonori Tsuzuki
Japan
Theo van der Kwast
Canada
Murali Varma
United Kingdom
Ming Zhou
USA
BLADDER EXPERT PANEL
Cristina Magi-Galluzzi (Panel Leader)
USA
Mahul Amin
USA
Liang Cheng
USA
John Cheville
USA
Eva Comperat
France
Brett Delahunt
New Zealand
Jonathan Epstein
USA
David Grignon
USA
Donna Hansel
USA
Arndt Hartmann
Germany
Glen Kristiansen
Germany
Lakshmi Kunju
USA
Katia Leite
Brazil
Antonio Lopez-Beltran
Spain
Jesse McKenney
USA
George Netto
USA
Gladell Paner
USA
Chin Chen Pan
Taiwan
Hemamali Samaratunga
Australia
Jonathan Shanks
UK
Fabio Tavora
USA
Xiaodong Teng
China
Toyonori Tsuzuki
Japan
Ming Zhou
USA
KIDNEY EXPERT PANEL
Brett Delahunt (Panel Leader)
New Zealand
Mahul Amin
USA
Pete Argani
USA
Matteo Brunelli
Italy
Yingbei Chen
USA
John Cheville
USA
Eva Comperat
France
John Eble
USA
Andrew Evans
Canada
Stuart Fleming
UK
David Grignon
USA
Ondrej Hes
Czech republic
Katia Leite
Brazil
Cristina Magi-Galluzzi
USA
Guido Martignoni
Italy
Jesse McKenney
USA
Holger Moch
Switzerland
Chin-Chen Pan
Taiwan
Hemamali Samaratunga
Australia
Isabell Sesterhenn
USA
John Srigley
Canada
Fabio Tavora
USA
Satish Tickoo
USA
Ming Zhou
USA