Case ID: 779

Publication date: 28 Aug, 2015

Consensus grade: GS 4+3=7 (ISUP 3)

User Diagnosis Difficulty Comment
Pathologist 1 GS 4+3=7 (ISUP 3) Typical
Pathologist 2 GS 4+3=7 (ISUP 3) Typical
Pathologist 3 GS 4+3=7 (ISUP 3) Typical

Most is 4+4; top image has considerable pattern 3 in it

Pathologist 4 GS 4+3=7 (ISUP 3) Borderline higher

Difficult to judge percentage grade 3

Pathologist 5 GS 9-10 (ISUP 5) Borderline higher

4+5

Pathologist 6 GS 4+3=7 (ISUP 3) Typical
Pathologist 7 GS 4+4=8 (ISUP 4) Borderline lower
Pathologist 8 GS 4+3=7 (ISUP 3) Borderline higher

mostly fused and crbriform glands, a few discrete glands

Pathologist 9 GS 4+3=7 (ISUP 3) Borderline lower

difficult to estimate the amount of pattern 3 and 4 by images
need more low power pictures

Pathologist 10 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 11 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 12 GS 4+3=7 (ISUP 3) Typical
Pathologist 13 GS 4+3=7 (ISUP 3) Borderline higher

Appeared that more 5% of tumour was pattern 3, thus the pattern 3 should not be ignored. Tough case that could also be called 4+4 in my view.

Pathologist 14 GS 4+4=8 (ISUP 4) Typical

Comsidered GS 4+5, especially on the last image.

Pathologist 15 GS 4+4=8 (ISUP 4) Typical
Pathologist 16 GS 9-10 (ISUP 5) Typical
Pathologist 17 GS 4+3=7 (ISUP 3) Typical
Pathologist 18 GS 4+3=7 (ISUP 3) Typical
Pathologist 19 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 20 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 21 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 22 GS 4+3=7 (ISUP 3) Borderline lower
Pathologist 23 GS 4+4=8 (ISUP 4) Typical

I would not give a 5, beause I think these are tangentially cut glands

Pathologist 24 GS 4+4=8 (ISUP 4) Borderline higher
Pathologist 25 GS 4+4=8 (ISUP 4) Typical


Case description (by case creator):

A mixture of fused, poorly formed and cribriform glands.