Case ID: 685

Publication date: 27 Aug, 2015

Consensus grade: GS 3+4=7 (ISUP 2)

User Diagnosis Difficulty Comment
Pathologist 1 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 2 GS 3+4=7 (ISUP 2) Borderline higher

more small well-formed glands v. poorly formed glands

Pathologist 3 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 4 GS 4+3=7 (ISUP 3) Typical

Small lesion, i tend to downgrade a bit. i see still some separate true glands.

Pathologist 5 GS 3+4=7 (ISUP 2) Borderline higher

Poorly-formed and fused glands

Pathologist 6 GS 3+4=7 (ISUP 2) Typical
Pathologist 7 GS 3+4=7 (ISUP 2) Typical
Pathologist 8 GS 3+4=7 (ISUP 2) Typical
Pathologist 9 GS 3+3=6 (ISUP 1) Typical

atrophic G3

Pathologist 10 GS 3+3=6 (ISUP 1) Typical
Pathologist 11 GS 3+4=7 (ISUP 2) Typical
Pathologist 12 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 13 GS 4+4=8 (ISUP 4) Borderline higher

Not quite convinced that there is any definite pattern 5 - it could still be tangential sectioning focally.

Pathologist 14 GS 3+3=6 (ISUP 1) Typical
Pathologist 15 GS 3+4=7 (ISUP 2) Borderline lower
Pathologist 16 GS 3+4=7 (ISUP 2) Typical
Pathologist 17 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 18 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 19 GS 4+4=8 (ISUP 4) Borderline lower
Pathologist 20 GS 3+4=7 (ISUP 2) Borderline lower
Pathologist 21 GS 3+4=7 (ISUP 2) Typical

some of these glands have quite a lot of atypia, and are confluent, few cancer, but evil looking

Pathologist 22 GS 3+4=7 (ISUP 2) Typical

Good poorly formed glands

Pathologist 23 GS 3+3=6 (ISUP 1) Borderline higher
Pathologist 24 GS 4+3=7 (ISUP 3) Borderline lower
Pathologist 25 GS 3+4=7 (ISUP 2) Borderline lower


Case description (by case creator):

Minimal cancer but too many poorly formed glands to be overlooked.