Case ID: 635

Publication date: 27 Aug, 2015

Consensus grade: GS 9-10 (ISUP 5)

User Diagnosis Difficulty Comment
Pathologist 1 GS 4+4=8 (ISUP 4) Typical
Pathologist 2 GS 9-10 (ISUP 5) Typical
Pathologist 3 GS 9-10 (ISUP 5) Typical
Pathologist 4 GS 9-10 (ISUP 5) Borderline higher

Tricky to go with a 5 component or not

Pathologist 5 GS 9-10 (ISUP 5) Typical

Single tumor cells

Pathologist 6 GS 9-10 (ISUP 5) Typical
Pathologist 7 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 8 GS 4+4=8 (ISUP 4) Borderline higher

Is this post therapy?

Pathologist 9 GS 4+4=8 (ISUP 4) Typical

fused, abortive glands

Pathologist 10 GS 9-10 (ISUP 5) Borderline lower
Pathologist 11 GS 9-10 (ISUP 5) Borderline lower
Pathologist 12 GS 9-10 (ISUP 5) Typical

Anti androgen effect?

Pathologist 13 GS 9-10 (ISUP 5) Typical

GS 4+5+9

Pathologist 14 GS 9-10 (ISUP 5) Typical
Pathologist 15 GS 9-10 (ISUP 5) Typical
Pathologist 16 GS 9-10 (ISUP 5) Borderline higher
Pathologist 17 GS 9-10 (ISUP 5) Typical
Pathologist 18 GS 9-10 (ISUP 5) Typical
Pathologist 19 GS 9-10 (ISUP 5) Typical
Pathologist 20 GS 4+3=7 (ISUP 3) Typical

there are some independent looking cells, but I think they are just tangentially cut

Pathologist 21 GS 9-10 (ISUP 5) Typical
Pathologist 22 GS 9-10 (ISUP 5) Typical
Pathologist 23 GS 9-10 (ISUP 5) Typical


Case description (by case creator):

Scattered pale single cells in the stroma (GP5). There are also some cribriform or fused glands (GP4).