Case ID: 425

Publication date: 27 Aug, 2015

Consensus grade: GS 4+3=7 (ISUP 3)

User Diagnosis Difficulty Comment
Pathologist 1 GS 4+3=7 (ISUP 3) Typical
Pathologist 2 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 3 GS 3+4=7 (ISUP 2) Typical
Pathologist 4 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 5 GS 3+4=7 (ISUP 2) Typical
Pathologist 6 GS 4+3=7 (ISUP 3) Typical
Pathologist 7 GS 3+4=7 (ISUP 2) Borderline higher

Possible single cells but I favored them to be part of fused glands

Pathologist 8 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 9 GS 4+3=7 (ISUP 3) Typical
Pathologist 10 GS 4+3=7 (ISUP 3) Typical

Approx. 80% pattern 4. Some glomerulations present.

Pathologist 11 GS 3+4=7 (ISUP 2) Borderline higher

these cribriform glands are considered G4

Pathologist 12 GS 4+3=7 (ISUP 3) Typical
Pathologist 13 GS 4+3=7 (ISUP 3) Typical
Pathologist 14 GS 4+3=7 (ISUP 3) Typical
Pathologist 15 GS 4+3=7 (ISUP 3) Typical
Pathologist 16 GS 4+3=7 (ISUP 3) Typical
Pathologist 17 GS 4+3=7 (ISUP 3) Typical
Pathologist 18 GS 4+3=7 (ISUP 3) Typical
Pathologist 19 GS 3+4=7 (ISUP 2) Typical
Pathologist 20 GS 3+4=7 (ISUP 2) Typical

4+3 could also be an option, but I think thereis more 3 than 4

Pathologist 21 GS 4+3=7 (ISUP 3) Typical
Pathologist 22 GS 4+3=7 (ISUP 3) Typical
Pathologist 23 GS 4+3=7 (ISUP 3) Typical
Pathologist 24 GS 4+3=7 (ISUP 3) Borderline lower


Case description (by case creator):

Gleason pattern 4 with glomeruloid bodies. There is also a GP 3 component.