Case ID: 242

Publication date: 05 Jun, 2015

Consensus grade: GS 9-10 (ISUP 5)

User Diagnosis Difficulty Comment
Pathologist 1 GS 9-10 (ISUP 5) Typical

4+5

Pathologist 2 GS 9-10 (ISUP 5) Typical
Pathologist 3 GS 9-10 (ISUP 5) Typical
Pathologist 4 GS 9-10 (ISUP 5) Borderline higher

v. 448

Pathologist 5 GS 4+4=8 (ISUP 4) Typical
Pathologist 6 GS 4+3=7 (ISUP 3) Borderline lower

always difficult these cases, I would go for a 4+3, because still have the impression to see some glands

Pathologist 7 GS 4+3=7 (ISUP 3) Typical
Pathologist 8 GS 9-10 (ISUP 5) Typical
Pathologist 9 GS 4+4=8 (ISUP 4) Borderline lower
Pathologist 10 GS 9-10 (ISUP 5) Borderline lower

?4+4

Pathologist 11 GS 9-10 (ISUP 5) Typical
Pathologist 12 GS 4+4=8 (ISUP 4) Typical
Pathologist 13 GS 9-10 (ISUP 5) Typical
Pathologist 14 GS 9-10 (ISUP 5) Borderline lower
Pathologist 15 GS 9-10 (ISUP 5) Borderline lower
Pathologist 16 GS 9-10 (ISUP 5) Borderline higher

Gleason score 4 + 5

Pathologist 17 GS 4+4=8 (ISUP 4) Borderline lower

Mainly poorly formed or fused glands. Some apparent poorly formed glands could be tangentially cut 3

Pathologist 18 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 19 GS 9-10 (ISUP 5) Typical
Pathologist 20 GS 9-10 (ISUP 5) Typical
Pathologist 21 GS 9-10 (ISUP 5) Borderline higher
Pathologist 22 GS 9-10 (ISUP 5) Borderline higher
Pathologist 23 GS 4+4=8 (ISUP 4) Typical
Pathologist 24 GS 9-10 (ISUP 5) Typical
Pathologist 25 GS 9-10 (ISUP 5) Typical


Case description (by case creator):

4+5=9 where the GP5 component infiltrates diffusely in strands and single cells.