Case ID: 752
Publication date: 28 Aug, 2015
Consensus grade: GS 3+4=7 (ISUP 2)
Show diagnosis by expert panel members| User | Diagnosis | Difficulty | Comment |
|---|---|---|---|
| Pathologist 1 | GS 3+4=7 (ISUP 2) | Borderline lower | |
| Pathologist 2 | GS 3+3=6 (ISUP 1) | Borderline higher |
Cribriform here is G3, not 4, by classic Gleason grading. |
| Pathologist 3 | GS 3+3=6 (ISUP 1) | Borderline higher |
Plus high grade PIN, possibly (looks like grade 4). |
| Pathologist 4 | GS 3+3=6 (ISUP 1) | Borderline higher |
Interpreted the "fused" gland as HGPIN |
| Pathologist 5 | GS 3+3=6 (ISUP 1) | Borderline lower |
HG-PIN in 1 gland space |
| Pathologist 6 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 7 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 8 | GS 3+4=7 (ISUP 2) | Borderline higher |
mostly G3, one G4 cribriform gland |
| Pathologist 9 | GS 3+4=7 (ISUP 2) | Borderline lower |
need immunohistochemistry to clarify the cribriform glands loose basal cells or not |
| Pathologist 10 | GS 3+3=6 (ISUP 1) | Borderline higher | |
| Pathologist 11 | GS 3+4=7 (ISUP 2) | Borderline lower | |
| Pathologist 12 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 13 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 14 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 15 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 16 | GS 3+3=6 (ISUP 1) | Borderline higher | |
| Pathologist 17 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 18 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 19 | GS 3+4=7 (ISUP 2) | Typical | |
| Pathologist 20 | GS 3+4=7 (ISUP 2) | Borderline lower | |
| Pathologist 21 | GS 3+3=6 (ISUP 1) | Borderline higher |
?intraductal cribriform. Not quite enough for fusion/poorly formed. |
| Pathologist 22 | GS 3+3=6 (ISUP 1) | Typical |
3+4 also a good option, but I wonder if the high magnifiation cribriform is not a kind of IDC, therefor i remain on 6 + a comment about IDC |
| Pathologist 23 | GS 3+4=7 (ISUP 2) | Typical |
Cribriform focus may be IDC? |
| Pathologist 24 | GS 3+4=7 (ISUP 2) | Borderline lower |
Case description (by case creator):
Mostly GP3 but there is a poorly circumscribed cribriform gland which justifies GP4. An immunostain for p63/AMACR was done (not shown here) and this particular gland was negative for basal cells.
