Case ID: 664

Publication date: 27 Aug, 2015

Consensus grade: GS 9-10 (ISUP 5)

User Diagnosis Difficulty Comment
Pathologist 1 GS 9-10 (ISUP 5) Typical
Pathologist 2 GS 9-10 (ISUP 5) Borderline lower
Pathologist 3 GS 9-10 (ISUP 5) Typical

5+4

Pathologist 4 GS 9-10 (ISUP 5) Typical
Pathologist 5 GS 9-10 (ISUP 5) Typical
Pathologist 6 GS 9-10 (ISUP 5) Typical
Pathologist 7 GS 4+4=8 (ISUP 4) Typical
Pathologist 8 GS 4+4=8 (ISUP 4) Borderline higher

still recognizable as adenocarcinoma

Pathologist 9 GS 9-10 (ISUP 5) Typical
Pathologist 10 GS 9-10 (ISUP 5) Typical
Pathologist 11 GS 9-10 (ISUP 5) Borderline higher

GS 4+5=9 (90% pattern 4). Also some low volume grade 3 in last image.

Pathologist 12 GS 9-10 (ISUP 5) Typical
Pathologist 13 GS 9-10 (ISUP 5) Typical
Pathologist 14 GS 4+3=7 (ISUP 3) Borderline lower
Pathologist 15 GS 9-10 (ISUP 5) Typical
Pathologist 16 GS 9-10 (ISUP 5) Typical
Pathologist 17 GS 9-10 (ISUP 5) Typical
Pathologist 18 GS 9-10 (ISUP 5) Typical
Pathologist 19 GS 9-10 (ISUP 5) Typical

confluent and sheet like

Pathologist 20 GS 9-10 (ISUP 5) Typical
Pathologist 21 GS 9-10 (ISUP 5) Typical
Pathologist 22 GS 9-10 (ISUP 5) Typical
Pathologist 23 GS 9-10 (ISUP 5) Typical


Case description (by case creator):

Large sheets of fused glands but also sheets of tightly packed pale single cells.