Case ID: 628

Publication date: 27 Aug, 2015

Consensus grade: GS 3+3=6 (ISUP 1)

User Diagnosis Difficulty Comment
Pathologist 1 GS 3+4=7 (ISUP 2) Borderline lower
Pathologist 2 GS 3+3=6 (ISUP 1) Borderline higher
Pathologist 3 GS 3+4=7 (ISUP 2) Typical
Pathologist 4 GS 3+3=6 (ISUP 1) Typical
Pathologist 5 GS 3+3=6 (ISUP 1) Typical
Pathologist 6 GS 3+3=6 (ISUP 1) Borderline lower

Easy 3

Pathologist 7 GS 3+3=6 (ISUP 1) Typical

Focus of HPIN also noted.

Pathologist 8 GS 3+3=6 (ISUP 1) Typical
Pathologist 9 GS 3+4=7 (ISUP 2) Borderline lower

The slight complexity of the mucinous fibroplasia is leading me to diagnose a minor GP4 component.

Pathologist 10 GS 3+3=6 (ISUP 1) Typical

predominantly discrete glands

Pathologist 11 GS 3+4=7 (ISUP 2) Borderline lower

Small cribriform element. therefore must be pattern 4 as per Chicago 2014 consensus recomendations

Pathologist 12 GS 3+3=6 (ISUP 1) Typical
Pathologist 13 GS 3+3=6 (ISUP 1) Typical

Some mucinous fibroplasia present.

Pathologist 14 GS 3+3=6 (ISUP 1) Borderline higher
Pathologist 15 GS 3+4=7 (ISUP 2) Typical
Pathologist 16 GS 3+4=7 (ISUP 2) Typical
Pathologist 17 GS 3+3=6 (ISUP 1) Borderline higher

Mucnous fibroplasia

Pathologist 18 GS 3+3=6 (ISUP 1) Borderline higher
Pathologist 19 GS 3+3=6 (ISUP 1) Typical
Pathologist 20 GS 3+3=6 (ISUP 1) Typical

Maybe on the right one focus of IDC or PIN, not easy to say, would make a comment, or do IHC

Pathologist 21 GS 3+3=6 (ISUP 1) Typical
Pathologist 22 GS 3+3=6 (ISUP 1) Borderline higher
Pathologist 23 GS 3+3=6 (ISUP 1) Typical


Case description (by case creator):

Well-formed cancer glands that infiltrate among benign glands. There are some collagenous micronodules but the adjacent glands do not seem to be disrupted.