Case ID: 605

Publication date: 27 Aug, 2015

Consensus grade: GS 4+3=7 (ISUP 3)

User Diagnosis Difficulty Comment
Pathologist 1 GS 4+3=7 (ISUP 3) Typical
Pathologist 2 GS 4+3=7 (ISUP 3) Typical
Pathologist 3 GS 4+4=8 (ISUP 4) Typical

Less than 5% G3.

Pathologist 4 GS 4+3=7 (ISUP 3) Typical
Pathologist 5 GS 4+4=8 (ISUP 4) Borderline lower
Pathologist 6 GS 4+3=7 (ISUP 3) Borderline lower

Difficult to assume amounts of 3 and 4 by images

Pathologist 7 GS 4+3=7 (ISUP 3) Typical
Pathologist 8 GS 4+3=7 (ISUP 3) Typical

Primarily cribriform

Pathologist 9 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 10 GS 4+4=8 (ISUP 4) Typical
Pathologist 11 GS 4+4=8 (ISUP 4) Typical
Pathologist 12 GS 4+3=7 (ISUP 3) Typical

mostly large cribriform glands, a few discrete glands

Pathologist 13 GS 9-10 (ISUP 5) Borderline lower

Would like to see at least 3 levels for this biopsy to confirm/exclude presence of pattern 5

Pathologist 14 GS 4+4=8 (ISUP 4) Typical

Ductal

Pathologist 15 GS 4+3=7 (ISUP 3) Typical

90-95% pattern 4.

Pathologist 16 GS 4+4=8 (ISUP 4) Typical
Pathologist 17 GS 4+3=7 (ISUP 3) Typical
Pathologist 18 GS 9-10 (ISUP 5) Borderline higher
Pathologist 19 GS 4+3=7 (ISUP 3) Borderline higher
Pathologist 20 GS 4+3=7 (ISUP 3) Typical
Pathologist 21 GS 4+3=7 (ISUP 3) Borderline lower

Some of cribriform may be intraductal

Pathologist 22 GS 4+3=7 (ISUP 3) Borderline lower

quite convinced that this patient should be treated like a 8, but there are too many 3 elements. Would make a comment on the stroma, scleroti stroma in my experience bad prognostic fator

Pathologist 23 GS 4+3=7 (ISUP 3) Typical
Pathologist 24 GS 4+4=8 (ISUP 4) Typical
Pathologist 25 GS 4+3=7 (ISUP 3) Typical


Case description (by case creator):

Areas with cribriform GP4 and other areas with poorly formed glands mixed with well-formed glands. There are also some seemingly solid strips of epithelium but these may possibly be tangential cuts.