Case ID: 322

Publication date: 05 Jun, 2015

Consensus grade: GS 3+4=7 (ISUP 2)

User Diagnosis Difficulty Comment
Pathologist 1 GS 3+4=7 (ISUP 2) Typical
Pathologist 2 GS 3+4=7 (ISUP 2) Typical
Pathologist 3 GS 3+4=7 (ISUP 2) Typical
Pathologist 4 GS 3+4=7 (ISUP 2) Borderline lower
Pathologist 5 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 6 GS 3+4=7 (ISUP 2) Typical

some glomerulation, some badly confluent glands, nuclear atypia moderate

Pathologist 7 GS 3+4=7 (ISUP 2) Borderline lower

Hard to tell if there are fused glands or not (bottom of third image)

Pathologist 8 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 9 GS 3+4=7 (ISUP 2) Typical
Pathologist 10 GS 4+3=7 (ISUP 3) Borderline lower
Pathologist 11 GS 4+3=7 (ISUP 3) Borderline lower

Difficult to assess proportion of G3 vs G4

Pathologist 12 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 13 GS 3+4=7 (ISUP 2) Typical
Pathologist 14 GS 3+4=7 (ISUP 2) Typical
Pathologist 15 GS 3+4=7 (ISUP 2) Borderline lower

Well formed glands and fused glands.

Pathologist 16 GS 3+4=7 (ISUP 2) Typical
Pathologist 17 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 18 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 19 GS 4+3=7 (ISUP 3) Borderline higher

90-95% pattern 4. It can be hard to estimate percentages when the images have overlapping areas - have to do some mental subtraction.

Pathologist 20 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 21 GS 3+4=7 (ISUP 2) Typical
Pathologist 22 GS 3+4=7 (ISUP 2) Borderline higher
Pathologist 23 GS 4+3=7 (ISUP 3) Typical
Pathologist 24 GS 3+4=7 (ISUP 2) Typical


Case description (by case creator):

Glandular fusion makes GP4.