Case ID: 164
Publication date: 18 Nov, 2015
Consensus grade: Carcinoma in situ (CIS)
Show diagnosis by expert panel members| User | Diagnosis | Difficulty | Comment |
|---|---|---|---|
| Pathologist 1 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 2 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 3 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 4 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 5 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 6 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 7 | Carcinoma in situ (CIS) | Typical |
Hard to judge IHCH without knowing antibody... |
| Pathologist 8 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 9 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 10 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 11 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 12 | Carcinoma in situ (CIS) | Borderline higher | |
| Pathologist 13 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 14 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 15 | Carcinoma in situ (CIS) | Typical |
No specific comment. |
| Pathologist 16 | Carcinoma in situ (CIS) | Bordering on lower | |
| Pathologist 17 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 18 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 19 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 20 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 21 | Atypia/dysplasia | Bordering on higher | |
| Pathologist 22 | Carcinoma in situ (CIS) | Typical |
Case description (by case creator):
This case illustrates urothelial carcinoma in-situ (CIS). URO3 immunohistochemistry is shown (CK20 = red, p53 = brown, CD44 = blue). The diagnosis is based primarily on morphology and immunohistochemistry cannot separate CIS from dysplasia. Adjacent normal urothelium is shown for comparison.
