Case ID: 128

Publication date: 13 Dec, 2015

Consensus grade: MiT Family translocation carcinoma

User Diagnosis Difficulty Comment
Pathologist 1 MiT Family translocation carcinoma Not typical

difficult

Pathologist 2 MiT Family translocation carcinoma Typical
Pathologist 3 MiT Family translocation carcinoma Not typical
Pathologist 4 Insufficient tumor for diagnosis Not typical
Pathologist 5 Renal cell carcinoma, unclassified Not typical

over photo shopped

Pathologist 6 Oncocytic papillary RCC Not typical
Pathologist 7 MiT Family translocation carcinoma Typical

Prob t(6;11)

Would not grade this

Pathologist 8 MiT Family translocation carcinoma Typical
Pathologist 9 MiT Family translocation carcinoma Not typical
Pathologist 10 Chromophobe RCC Not typical

More representative images would be helpful.

Pathologist 11 Other Not typical
Pathologist 12 MiT Family translocation carcinoma Typical
Pathologist 13 MiT Family translocation carcinoma Typical

t(6;11)

Pathologist 14 MiT Family translocation carcinoma Typical
Pathologist 15 MiT Family translocation carcinoma Typical

t(6,11) translocation RCC

Pathologist 16 MiT Family translocation carcinoma Typical
Pathologist 17 MiT Family translocation carcinoma Typical
Pathologist 18 MiT Family translocation carcinoma Typical

images too dark and not sharp enough

Pathologist 19 MiT Family translocation carcinoma Typical

TFEB

Pathologist 20 MiT Family translocation carcinoma Typical
Pathologist 21 MiT Family translocation carcinoma Typical

t(6;11) translocation



Case description (by case creator):

MiT family translocation renal cell carcinoma. t(6;11) translocation
Section courtesy of Dr P Argani